Description

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17). Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.


Clinical trials

NCT03302403 - Hepatocellular Carcinoma, Pancreatic Cancer


Target gene expression

The following plot describes the expression, in different tissues and TCGA cancers, of the different isoforms of the gene TNFRSF17.


Target essentiality


Protein properties

The following plot describes the target topology, highlighting the position of the endo-, ecto- and transmembrane domains, as well as the position of a signal peptide, when present.